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Acute appendicitis, with complications

DOID EFO MESH SNOMED Endpoint Browser PheWeb

APPENDACUT_COMPLIC

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K35.0, K35.1
Hospital discharge: ICD-9 540[0-1]
Hospital discharge: ICD-8 540
Hospital discharge: excluded ICD-8 54090|54099
Cause of death: ICD-10 K35.0, K35.1
Cause of death: ICD-9 540[0-1]
Cause of death: ICD-8 540
Cause of death: excluded ICD-8 54090|54099

2 out of 7 registries used, show all original rules.

7572

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Check minimum number of events None

7572

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Include endpoints None

7572

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Remove individuals based on genotype QC

7358

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APPENDACUT_COMPLIC

Control definitions

Control exclude K11_APPENDIX

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 7358 3511 3847
Unadjusted prevalence (%) 1.79 1.52 2.12
Mean age at first event (years) 36.35 34.05 38.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.17 [0.93, 1.49] 1.9e-1 863
15 years 0.01 0.93 [0.77, 1.13] 4.8e-1 359
5 years 0.00 1.26 [1.02, 1.56] 3.0e-2 132
1 year 0.00 2.77 [2.05, 3.75] 3.6e-11 52

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: APPENDACUT_COMPLIC – Acute appendicitis, with complications
GWS hits: 5

Survival analyses between endpoints

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Plot

before Acute appendicitis, with complications
after Acute appendicitis, with complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute appendicitis, with complications

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Endpoint not on priority list, no data to show.