Tobacco use

Z21_TOBAC_USE

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 Z72.0
Cause of death: ICD-10 Z72.0

2 out of 7 registries used, show all original rules.

1520

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Check minimum number of events None

1520

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Include endpoints None

1520

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Remove individuals based on genotype QC

1454

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Z21_TOBAC_USE

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
Special TOBACCO_USE
First used in FinnGen datafreeze DF4
Parent code in ICD-10 Z72

Summary Statistics

Key figures

All Female Male
Number of individuals 1454 765 689
Unadjusted prevalence (%) 0.35 0.33 0.38
Mean age at first event (years) 52.42 46.92 58.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.21 10.94 [5.72, 20.90] 4.4e-13 171
15 years 0.03 3.92 [2.24, 6.86] 1.7e-6 50
5 years 0.02 12.66 [8.23, 19.48] 7.4e-31 74
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: Z21_TOBAC_USE – Tobacco use
GWS hits:

Survival analyses between endpoints

Plot

before Tobacco use
after Tobacco use

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Tobacco use

Endpoint not on priority list, no data to show.