≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Ulcerative ileocolitis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

ULCERILEO

Crohn's disease: A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K51.1
Cause of death: ICD-10 K51.1

2 out of 7 registries used, show all original rules.

1411

diagram downward connector

Check minimum number of events None

1411

diagram downward connector

Include endpoints None

1411

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

1379

diagram downward connector
ULCERILEO

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Ileocolitis ulcerosa [chronica]

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 1379 722 657
Unadjusted prevalence (%) 0.33 0.31 0.36
Mean age at first event (years) 42.99 40.60 45.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 3.64 [1.76, 7.53] 5.0e-4 73
15 years 0.02 2.46 [1.41, 4.30] 1.6e-3 32
5 years 0.01 4.47 [2.59, 7.71] 7.1e-8 20
1 year 0.00 11.19 [5.48, 22.83] 3.2e-11 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: ULCERILEO – Ulcerative ileocolitis
GWS hits: 2

Survival analyses between endpoints

↥

Plot

before Ulcerative ileocolitis
after Ulcerative ileocolitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ulcerative ileocolitis

↥

Endpoint not on priority list, no data to show.