Ulcerative enterocolitis

ULCERENTER

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K51.0
Cause of death: ICD-10 K51.0

2 out of 7 registries used, show all original rules.

1040

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Check minimum number of events None

1040

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Include endpoints None

1040

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Remove individuals based on genotype QC

1010

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ULCERENTER

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Enterocolitis ulcerosa [chronica]

Summary Statistics

Key figures

All Female Male
Number of individuals 1010 538 472
Unadjusted prevalence (%) 0.25 0.23 0.26
Mean age at first event (years) 43.44 39.23 48.22

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.67 [2.07, 6.49] 8.0e-6 100
15 years 0.02 2.24 [1.36, 3.69] 1.5e-3 40
5 years 0.01 4.29 [2.80, 6.57] 2.2e-11 27
1 year 0.00 10.67 [5.75, 19.78] 5.9e-14 13

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ULCERENTER – Ulcerative enterocolitis
GWS hits: 3

Survival analyses between endpoints

Plot

before Ulcerative enterocolitis
after Ulcerative enterocolitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ulcerative enterocolitis

Endpoint not on priority list, no data to show.