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severe traumatic brain injury, does not include concussion

MESH Endpoint Browser PheWeb

TRAUMBRAIN_NONCONCUS

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 S06.2, S06.3, S06.4, S06.5, S06.6, S06.7
Hospital discharge: ICD-9 85[1-2]
Hospital discharge: ICD-8 85[1-2]
Cause of death: ICD-10 S06.2, S06.3, S06.4, S06.5, S06.6, S06.7
Cause of death: ICD-9 85[1-2]
Cause of death: ICD-8 85[1-2]

2 out of 7 registries used, show all original rules.

7662

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Check minimum number of events None

7662

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Include endpoints None

7662

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Remove individuals based on genotype QC

7429

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TRAUMBRAIN_NONCONCUS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 7429 2485 4944
Unadjusted prevalence (%) 1.80 1.08 2.72
Mean age at first event (years) 59.70 58.07 60.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 4.32 [3.34, 5.57] 3.2e-29 2123
15 years 0.01 1.80 [1.48, 2.19] 3.5e-9 596
5 years 0.01 4.17 [3.57, 4.88] 1.6e-71 545
1 year 0.01 25.64 [22.10, 29.74] <1e-100 815

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: TRAUMBRAIN_NONCONCUS – severe traumatic brain injury, does not include concussion
GWS hits: 1

Survival analyses between endpoints

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Plot

before severe traumatic brain injury, does not include concussion
after severe traumatic brain injury, does not include concussion

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after severe traumatic brain injury, does not include concussion

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Endpoint not on priority list, no data to show.