Small fibre neuropathy

SFN

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G60.8, G62.8, G63.3*
Cause of death: ICD-10 G60.8, G62.8, G63.3*

2 out of 7 registries used, show all original rules.

708

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Check minimum number of events None

708

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Include endpoints None

708

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Remove individuals based on genotype QC

683

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SFN

Control definitions

Control exclude G6_POLYNEU

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 683 296 387
Unadjusted prevalence (%) 0.17 0.13 0.21
Mean age at first event (years) 62.10 59.52 64.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 6.24 [3.73, 10.42] 2.9e-12 98
15 years 0.02 2.43 [1.37, 4.32] 2.4e-3 35
5 years 0.01 5.66 [3.17, 10.11] 4.8e-9 40
1 year 0.00 13.71 [7.60, 24.73] 3.3e-18 21

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: SFN – Small fibre neuropathy
GWS hits:

Survival analyses between endpoints

Plot

before Small fibre neuropathy
after Small fibre neuropathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Small fibre neuropathy

Endpoint not on priority list, no data to show.