Statin medication

RX_STATIN

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC C10AA

1 out of 7 registries used, show all original rules.

149452

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Check minimum number of events

Min. number of events 3

149452

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Include endpoints None

149452

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Remove individuals based on genotype QC

144672

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RX_STATIN

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 144672 66618 78054
Unadjusted prevalence (%) 35.12 28.93 42.95
Mean age at first event (years) 59.52 59.74 59.33

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.42 [1.32, 1.53] 1.1e-21 20892
15 years 0.01 1.16 [1.09, 1.24] 6.0e-6 11677
5 years 0.00 1.34 [1.26, 1.43] 6.8e-21 3581
1 year 0.00 0.88 [0.77, 0.99] 4.1e-2 398

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_STATIN – Statin medication
GWS hits: 178

Survival analyses between endpoints

Plot

before Statin medication
after Statin medication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Statin medication