Biological medication for rheuma

Endpoint Browser PheWeb

RX_RHEUMA_BIOLOGICAL

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC L04AA24|L04AC03|L04AB04|L04AB01|L04AB06|L04AB02|L04AB05|L04AA26|L01XC02|L04AC10|L04AC07|L04AC05

1 out of 7 registries used, show all original rules.

5294

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Check minimum number of events

Min. number of events 3

5294

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Include endpoints None

5294

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Remove individuals based on genotype QC

5117

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RX_RHEUMA_BIOLOGICAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

NAME	RX_RHEUMA_BIOLOGICAL
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC	L04AA24\|L04AC03\|L04AB04\|L04AB01\|L04AB06\|L04AB02\|L04AB05\|L04AA26\|L01XC02\|L04AC10\|L04AC07\|L04AC05
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Biological medication for rheuma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	5117	3157	1960
Unadjusted prevalence (%)	1.24	1.37	1.08
Mean age at first event (years)	46.91	46.66	47.32

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	2.99 [1.31, 6.84]	9.3e-3	92
15 years	0.02	2.02 [0.87, 4.67]	1.0e-1	62
5 years	0.00	1.73 [0.87, 3.48]	1.2e-1	19
1 year	0.00	5.16 [2.40, 11.10]	2.7e-5	11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_RHEUMA_BIOLOGICAL – Biological medication for rheuma
GWS hits: 4

Survival analyses between endpoints

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Plot

before Biological medication for rheuma
after Biological medication for rheuma

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Table

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Drugs most likely to be purchased after Biological medication for rheuma

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Endpoint not on priority list, no data to show.