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First line medication for Crohn's disease

Endpoint Browser PheWeb

RX_CROHN_1STLINE

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC A07EC|H02AB

1 out of 7 registries used, show all original rules.

90340

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Check minimum number of events

Min. number of events 3

90340

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Include endpoints None

90340

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Remove individuals based on genotype QC

87508

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RX_CROHN_1STLINE

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 87508 51133 36375
Unadjusted prevalence (%) 21.24 22.21 20.01
Mean age at first event (years) 50.68 47.49 55.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.54 [2.33, 2.78] 7.0e-98 13437
15 years 0.01 1.67 [1.54, 1.80] 7.6e-38 5451
5 years 0.00 3.63 [3.40, 3.88] <1e-100 3863
1 year 0.00 6.23 [5.65, 6.88] <1e-100 1286

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_CROHN_1STLINE – First line medication for Crohn's disease
GWS hits: 40

Survival analyses between endpoints

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Plot

before First line medication for Crohn's disease
after First line medication for Crohn's disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after First line medication for Crohn's disease

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Endpoint not on priority list, no data to show.