Codeine or tramadol medication

RX_CODEINE_TRAMADOL

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC N02A02|N02AJ0|N02AJ1[3-5]|N02AA59|N02AA79

1 out of 7 registries used, show all original rules.

68924

diagram downward connector
diagram bullet

Check minimum number of events

Min. number of events 3

68924

diagram downward connector

Include endpoints None

68924

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

66771

diagram downward connector
RX_CODEINE_TRAMADOL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 66771 38776 27995
Unadjusted prevalence (%) 16.21 16.84 15.40
Mean age at first event (years) 54.03 52.08 56.73

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.55 [3.15, 4.00] 6.1e-97 5211
15 years 0.02 2.27 [2.01, 2.56] 6.4e-40 3214
5 years 0.00 3.05 [2.75, 3.38] 1.1e-98 1644
1 year 0.00 3.36 [2.90, 3.89] 9.0e-58 330

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_CODEINE_TRAMADOL – Codeine or tramadol medication
GWS hits: 9

Survival analyses between endpoints

Plot

before Codeine or tramadol medication
after Codeine or tramadol medication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Codeine or tramadol medication

Endpoint not on priority list, no data to show.