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Reactive arthropathies, FINNGEN

DOID EFO MESH SNOMED Endpoint Browser PheWeb

RHEUMA_ARHTROPAT_REACTIVE

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

2426

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Remove individuals based on genotype QC

2351

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RHEUMA_ARHTROPAT_REACTIVE

Control definitions

Control exclude RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2351 1333 1018
Unadjusted prevalence (%) 0.57 0.58 0.56
Mean age at first event (years) 46.52 44.28 49.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.06 [0.48, 2.36] 8.8e-1 174
15 years 0.01 0.84 [0.46, 1.53] 5.6e-1 73
5 years 0.00 1.70 [0.98, 2.94] 5.7e-2 38
1 year 0.00 2.58 [1.24, 5.35] 1.1e-2 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RHEUMA_ARHTROPAT_REACTIVE – Reactive arthropathies, FINNGEN
GWS hits: 1

Survival analyses between endpoints

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Plot

before Reactive arthropathies, FINNGEN
after Reactive arthropathies, FINNGEN

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Reactive arthropathies, FINNGEN

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Endpoint not on priority list, no data to show.