Reactive arthropathies, FINNGEN

RHEUMA_ARHTROPAT_REACTIVE

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

Endpoint definition

FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector

Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

2351

diagram downward connector
RHEUMA_ARHTROPAT_REACTIVE

Control definitions

Control exclude RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2351 1333 1018
Unadjusted prevalence (%) 0.57 0.58 0.56
Mean age at first event (years) 46.52 44.28 49.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.06 [0.48, 2.36] 8.8e-1 174
15 years 0.01 0.84 [0.46, 1.53] 5.6e-1 73
5 years 0.00 1.70 [0.98, 2.94] 5.7e-2 38
1 year 0.00 2.58 [1.24, 5.35] 1.1e-2 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RHEUMA_ARHTROPAT_REACTIVE – Reactive arthropathies, FINNGEN
GWS hits: 1

Survival analyses between endpoints

Plot

before Reactive arthropathies, FINNGEN
after Reactive arthropathies, FINNGEN

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Reactive arthropathies, FINNGEN

Endpoint not on priority list, no data to show.