Septal defects

Q17_SEPTA_DEFEC

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 Q21.0, Q21.10, Q21.11, Q21.12, Q21.13, Q21.18, Q21.19, Q21.88, Q21.9
Hospital discharge: ICD-9 7454E|7454X|7454A|7455A|7456X|7456A|7458X|7459X
Hospital discharge: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
Hospital discharge: excluded ICD-9 758|7595|75683
Cause of death: ICD-10 Q21.0, Q21.10, Q21.11, Q21.12, Q21.13, Q21.18, Q21.19, Q21.88, Q21.9
Cause of death: ICD-9 7454E|7454X|7454A|7455A|7456X|7456A|7458X|7459X
Cause of death: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
Cause of death: excluded ICD-9 758|7595|75683

2 out of 7 registries used, show all original rules.

2034

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Check minimum number of events None

2034

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Include endpoints None

2034

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Remove individuals based on genotype QC

1950

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Q17_SEPTA_DEFEC

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 1950 1158 792
Unadjusted prevalence (%) 0.47 0.50 0.44
Mean age at first event (years) 34.35 33.19 36.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.07 [2.34, 7.07] 6.8e-7 101
15 years 0.02 2.59 [1.50, 4.45] 6.1e-4 52
5 years 0.01 4.39 [2.57, 7.52] 6.8e-8 25
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: Q17_SEPTA_DEFEC – Septal defects
GWS hits: 5

Survival analyses between endpoints

Plot

before Septal defects
after Septal defects

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Septal defects

Endpoint not on priority list, no data to show.