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Redundant prepuce, phimosis and paraphimosis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

N14_PHIMOSIS

phimosis: A condition in which there is constriction in the tip of the foreskin resulting in inability to fully retract the foreskin over the glans penis. Causes include balanoposthitis, balanitis xerotica obliterans, and untreated diabetes.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only males

189303

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Check conditions None

189303

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N47
Hospital discharge: ICD-9 605
Hospital discharge: ICD-8 605
Cause of death: ICD-10 N47
Cause of death: ICD-9 605
Cause of death: ICD-8 605

2 out of 7 registries used, show all original rules.

7814

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Check minimum number of events None

7814

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Include endpoints None

7814

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Remove individuals based on genotype QC

7595

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N14_PHIMOSIS

Control definitions

Control exclude N14_MALEGEN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N40-N51
Name in latin Praeputium redundans, phimosis sive paraphimosis

Summary Statistics

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Key figures

All Female Male
Number of individuals 7595 - 7595
Unadjusted prevalence (%) 1.84 - 4.18
Mean age at first event (years) 35.82 - 35.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.64 [1.95, 3.58] 4.0e-10 743
15 years 0.01 1.61 [1.23, 2.10] 5.3e-4 269
5 years 0.01 3.92 [3.10, 4.96] 5.0e-30 237
1 year 0.00 8.75 [6.71, 11.41] 1.4e-57 109

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_PHIMOSIS – Redundant prepuce, phimosis and paraphimosis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Redundant prepuce, phimosis and paraphimosis
after Redundant prepuce, phimosis and paraphimosis

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Drugs most likely to be purchased after Redundant prepuce, phimosis and paraphimosis

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Endpoint not on priority list, no data to show.