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Other specified disorders of kidney and ureter

DOID EFO MESH Endpoint Browser PheWeb

N14_OTHETNASKIDUR

renal artery obstruction: Narrowing or occlusion of the renal artery or arteries. It is due usually to atherosclerosis; fibromuscular dysplasia; thrombosis; embolism, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (hypertension, renovascular).

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N28.0, N28.8, N28.9
Hospital discharge: ICD-9 593[0-1]|5938
Hospital discharge: ICD-8 59322
Hospital discharge: excluded ICD-8 5938B
Cause of death: ICD-10 N28.0, N28.8, N28.9
Cause of death: ICD-9 593[0-1]|5938
Cause of death: ICD-8 59322
Cause of death: excluded ICD-8 5938B

2 out of 7 registries used, show all original rules.

977

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Check minimum number of events None

977

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Include endpoints None

977

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Remove individuals based on genotype QC

948

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N14_OTHETNASKIDUR

Control definitions

Control exclude N14_KIDUROTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 948 504 444
Unadjusted prevalence (%) 0.23 0.22 0.24
Mean age at first event (years) 50.81 46.93 55.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.15 7.91 [5.51, 11.38] 5.6e-29 151
15 years 0.02 3.14 [2.10, 4.70] 2.9e-8 50
5 years 0.01 5.63 [3.07, 10.31] 2.2e-8 48
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_OTHETNASKIDUR – Other specified disorders of kidney and ureter
GWS hits:

Survival analyses between endpoints

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Plot

before Other specified disorders of kidney and ureter
after Other specified disorders of kidney and ureter

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Drugs most likely to be purchased after Other specified disorders of kidney and ureter

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Endpoint not on priority list, no data to show.