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Male infertility

DOID EFO MESH SNOMED Endpoint Browser PheWeb

N14_MALEINFERT

male infertility: The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only males

189303

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Check conditions None

189303

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N46
Hospital discharge: ICD-9 606
Hospital discharge: ICD-8 606
Cause of death: ICD-10 N46
Cause of death: ICD-9 606
Cause of death: ICD-8 606

2 out of 7 registries used, show all original rules.

1531

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Check minimum number of events None

1531

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Include endpoints None

1531

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Remove individuals based on genotype QC

1429

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N14_MALEINFERT

Control definitions

Control exclude N14_MALEGEN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N40-N51
Name in latin Infertilitas masculina

Summary Statistics

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Key figures

All Female Male
Number of individuals 1429 - 1429
Unadjusted prevalence (%) 0.35 - 0.79
Mean age at first event (years) 34.58 - 34.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.62 [1.37, 5.00] 3.6e-3 37
15 years 0.01 1.61 [0.73, 3.55] 2.4e-1 11
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_MALEINFERT – Male infertility
GWS hits: 1

Survival analyses between endpoints

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Plot

before Male infertility
after Male infertility

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Male infertility

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Endpoint not on priority list, no data to show.