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Female infertility

DOID EFO MESH SNOMED Endpoint Browser PheWeb

N14_FEMALEINFERT

male infertility: The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only females

239906

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Check conditions None

239906

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N97
Cause of death: ICD-10 N97

2 out of 7 registries used, show all original rules.

11337

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Check minimum number of events None

11337

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Include endpoints

15553

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Remove individuals based on genotype QC

14758

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N14_FEMALEINFERT

Control definitions

Control exclude N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N80-N98
Name in latin Infertilitas feminae

Similar endpoints

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List of similar endpoints to Female infertility based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 14758 14758 -
Unadjusted prevalence (%) 3.58 6.41 -
Mean age at first event (years) 31.30 31.30 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.69 [0.51, 0.94] 1.8e-2 208
15 years 0.00 0.38 [0.25, 0.56] 1.7e-6 43
5 years 0.00 0.58 [0.32, 1.06] 7.8e-2 13
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_FEMALEINFERT – Female infertility
GWS hits: 4

Survival analyses between endpoints

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Plot

before Female infertility
after Female infertility

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Drugs most likely to be purchased after Female infertility

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Endpoint not on priority list, no data to show.