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Endometriosis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

N14_ENDOMETRIOSIS

endometriosis: The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only females

239906

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Check conditions None

239906

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N80
Hospital discharge: ICD-9 617
Hospital discharge: ICD-8 6253
Cause of death: ICD-10 N80
Cause of death: ICD-9 617
Cause of death: ICD-8 6253

2 out of 7 registries used, show all original rules.

17158

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Check minimum number of events None

17158

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Include endpoints

17158

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Remove individuals based on genotype QC

16588

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N14_ENDOMETRIOSIS

Control definitions

Control exclude N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N80-N98
Name in latin Endometriosis

Summary Statistics

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Key figures

All Female Male
Number of individuals 16588 16588 -
Unadjusted prevalence (%) 4.03 7.20 -
Mean age at first event (years) 37.38 37.38 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.45 [0.37, 0.55] 8.5e-15 636
15 years 0.00 0.28 [0.23, 0.36] 5.7e-28 165
5 years 0.00 0.23 [0.15, 0.34] 1.4e-12 27
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_ENDOMETRIOSIS – Endometriosis
GWS hits: 34

Survival analyses between endpoints

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Plot

before Endometriosis
after Endometriosis

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Drugs most likely to be purchased after Endometriosis

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Endpoint not on priority list, no data to show.