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Disorders resulting from impaired renal tubular function

DOID EFO MESH SNOMED Endpoint Browser PheWeb

N14_DISIMPAIRRENTUB

urinary system disease: A disease involving the renal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N25
Hospital discharge: ICD-9 588
Cause of death: ICD-10 N25
Cause of death: ICD-9 588

2 out of 7 registries used, show all original rules.

993

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Check minimum number of events None

993

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Include endpoints None

993

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Remove individuals based on genotype QC

952

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N14_DISIMPAIRRENTUB

Control definitions

Control exclude N14_KIDUROTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N25-N29
Name in latin Morbositates ex dysfunctione tubulari renali

Summary Statistics

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Key figures

All Female Male
Number of individuals 952 418 534
Unadjusted prevalence (%) 0.23 0.18 0.29
Mean age at first event (years) 56.38 54.26 58.04

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 6.63 [2.30, 19.10] 4.5e-4 172
15 years 0.02 3.09 [1.45, 6.59] 3.6e-3 45
5 years 0.02 11.92 [7.45, 19.06] 4.7e-25 83
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_DISIMPAIRRENTUB – Disorders resulting from impaired renal tubular function
GWS hits: 1

Survival analyses between endpoints

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Plot

before Disorders resulting from impaired renal tubular function
after Disorders resulting from impaired renal tubular function

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders resulting from impaired renal tubular function

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Endpoint not on priority list, no data to show.