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Calculus of kidney and ureter

DOID EFO MESH SNOMED Endpoint Browser PheWeb

N14_CALCUKIDUR

nephrolithiasis: The presence of a calculus in the pelvis of the kidney; this is most often composed of mineral salts and proteins.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N20
Hospital discharge: ICD-9 592
Hospital discharge: ICD-8 592
Cause of death: ICD-10 N20
Cause of death: ICD-9 592
Cause of death: ICD-8 592

2 out of 7 registries used, show all original rules.

11144

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Check minimum number of events None

11144

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Include endpoints None

11144

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Remove individuals based on genotype QC

10556

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N14_CALCUKIDUR

Control definitions

Control exclude N14_UROLITHIASIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N20-N23
Name in latin Nephrolithiasis et/sive ureterolithiasis

Summary Statistics

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Key figures

All Female Male
Number of individuals 10556 3666 6890
Unadjusted prevalence (%) 2.56 1.59 3.79
Mean age at first event (years) 50.63 46.19 53.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.93 [0.71, 1.22] 6.1e-1 1533
15 years 0.01 0.71 [0.56, 0.88] 2.4e-3 635
5 years 0.00 1.16 [0.94, 1.43] 1.6e-1 269
1 year 0.00 2.10 [1.60, 2.76] 9.5e-8 86

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_CALCUKIDUR – Calculus of kidney and ureter
GWS hits: 19

Survival analyses between endpoints

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Plot

before Calculus of kidney and ureter
after Calculus of kidney and ureter

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Drugs most likely to be purchased after Calculus of kidney and ureter

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Endpoint not on priority list, no data to show.