Acute nephritic syndrome

N14_ACUTENEPHRITIC

nephritis: Inflammation of renal tissue. [ NCIT:P378 ]

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N00#
Hospital discharge: ICD-9 580
Hospital discharge: ICD-8 580
Hospital discharge: excluded ICD-9 5804
Cause of death: ICD-10 N00#
Cause of death: ICD-9 580
Cause of death: ICD-8 580
Cause of death: excluded ICD-9 5804

2 out of 7 registries used, show all original rules.

665

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Check minimum number of events None

665

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Include endpoints None

665

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Remove individuals based on genotype QC

634

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N14_ACUTENEPHRITIC

Control definitions

Control exclude N14_GLOMERULAR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N00-N08
Name in latin Syndroma nephriticum acutum

Summary Statistics

Key figures

All Female Male
Number of individuals 634 254 380
Unadjusted prevalence (%) 0.15 0.11 0.21
Mean age at first event (years) 35.67 33.74 36.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.05 [1.03, 4.08] 4.0e-2 106
15 years 0.01 1.42 [0.82, 2.47] 2.1e-1 38
5 years 0.00 3.18 [1.90, 5.32] 1.1e-5 23
1 year 0.00 8.54 [4.38, 16.66] 3.2e-10 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_ACUTENEPHRITIC – Acute nephritic syndrome
GWS hits:

Survival analyses between endpoints

Plot

before Acute nephritic syndrome
after Acute nephritic syndrome

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute nephritic syndrome

Endpoint not on priority list, no data to show.