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Mucosal proctocolitis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

MUCOPROCT

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K51.5
Cause of death: ICD-10 K51.5

2 out of 7 registries used, show all original rules.

4679

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Check minimum number of events None

4679

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Include endpoints None

4679

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Remove individuals based on genotype QC

4530

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MUCOPROCT

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Proctocolitis mucosalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 4530 2270 2260
Unadjusted prevalence (%) 1.10 0.99 1.24
Mean age at first event (years) 44.48 42.07 46.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.46 [1.59, 3.80] 4.9e-5 229
15 years 0.01 1.89 [1.31, 2.72] 6.0e-4 124
5 years 0.00 2.51 [1.70, 3.70] 3.3e-6 55
1 year 0.00 5.43 [3.24, 9.10] 1.3e-10 23

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MUCOPROCT – Mucosal proctocolitis
GWS hits: 33

Survival analyses between endpoints

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Plot

before Mucosal proctocolitis
after Mucosal proctocolitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Mucosal proctocolitis

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Endpoint not on priority list, no data to show.