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Other disorders of the musculoskeletal system and connective tissue

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_MUSCULOSKELEOTH

musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M95-M99
Cause of death: ICD-10 M95-M99

2 out of 7 registries used, show all original rules.

3310

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Check minimum number of events None

3310

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Include endpoints

4622

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Remove individuals based on genotype QC

4439

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M13_MUSCULOSKELEOTH

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 4439 2476 1963
Unadjusted prevalence (%) 1.08 1.08 1.08
Mean age at first event (years) 50.55 49.42 51.98

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.23 [1.67, 2.97] 5.3e-8 472
15 years 0.01 1.14 [0.84, 1.54] 4.0e-1 165
5 years 0.00 2.29 [1.71, 3.06] 2.3e-8 111
1 year 0.00 4.11 [2.81, 6.02] 4.0e-13 38

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MUSCULOSKELEOTH – Other disorders of the musculoskeletal system and connective tissue
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other disorders of the musculoskeletal system and connective tissue
after Other disorders of the musculoskeletal system and connective tissue

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other disorders of the musculoskeletal system and connective tissue

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Endpoint not on priority list, no data to show.