Vitiligo

L12_VITILIGO

Vitiligo: Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L80
Hospital discharge: ICD-9 7090F
Hospital discharge: ICD-8 70905
Cause of death: ICD-10 L80
Cause of death: ICD-9 7090F
Cause of death: ICD-8 70905

2 out of 7 registries used, show all original rules.

307

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Check minimum number of events None

307

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Include endpoints None

307

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Remove individuals based on genotype QC

292

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L12_VITILIGO

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L80-L99
Name in latin Vitiligo

Summary Statistics

Key figures

All Female Male
Number of individuals 292 174 118
Unadjusted prevalence (%) 0.07 0.08 0.06
Mean age at first event (years) 45.91 44.35 48.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.15 7.78 [4.44, 13.62] 7.4e-13 19
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_VITILIGO – Vitiligo
GWS hits:

Survival analyses between endpoints

Plot

before Vitiligo
after Vitiligo

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Drugs most likely to be purchased after Vitiligo

Endpoint not on priority list, no data to show.