Seborrhoeic dermatitis

L12_SEBORRHOEIC

seborrheic dermatitis: A dermatitis that is an inflammatory skin condition resulting in flaky, white to yellowish scales on oily areas such as the scalp or inside the ear, which is caused due to a combination of an over production of skin oil and irritation from a yeast Malassezia furfur. The symptoms include itching, skin lesions and scales, redness, plaques and hair loss.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L21
Hospital discharge: ICD-9 690
Hospital discharge: ICD-8 690|70630
Cause of death: ICD-10 L21
Cause of death: ICD-9 690
Cause of death: ICD-8 690|70630

2 out of 7 registries used, show all original rules.

3049

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Check minimum number of events None

3049

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Include endpoints None

3049

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Remove individuals based on genotype QC

2949

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L12_SEBORRHOEIC

Control definitions

Control exclude L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L20-L30
Name in latin Eczema seborrhoicum

Summary Statistics

Key figures

All Female Male
Number of individuals 2949 1236 1713
Unadjusted prevalence (%) 0.72 0.54 0.94
Mean age at first event (years) 52.90 48.19 56.30

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.81 [1.75, 4.50] 1.8e-5 338
15 years 0.01 1.88 [1.26, 2.81] 1.9e-3 158
5 years 0.01 3.68 [2.65, 5.09] 5.0e-15 106
1 year 0.00 4.87 [3.12, 7.61] 3.4e-12 28

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_SEBORRHOEIC – Seborrhoeic dermatitis
GWS hits: 2

Survival analyses between endpoints

Plot

before Seborrhoeic dermatitis
after Seborrhoeic dermatitis

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Drugs most likely to be purchased after Seborrhoeic dermatitis

Endpoint not on priority list, no data to show.