Pyoderma gangrenosum

L12_PYODERMAGANGRENOSUM

pyoderma gangrenosum: ['An idiopathic, rapidly evolving, and severely debilitating disease occurring most commonly in association with chronic ulcerative colitis. It is characterized by the presence of boggy, purplish ulcers with undermined borders, appearing mostly on the legs. The majority of cases are in people between 40 and 60 years old. Its etiology is unknown.']

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L88
Cause of death: ICD-10 L88

2 out of 7 registries used, show all original rules.

176

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Check minimum number of events None

176

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Include endpoints None

176

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Remove individuals based on genotype QC

168

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L12_PYODERMAGANGRENOSUM

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L80-L99
Name in latin Pyoderma gangraenosum

Summary Statistics

Key figures

All Female Male
Number of individuals 168 105 63
Unadjusted prevalence (%) 0.04 0.05 0.03
Mean age at first event (years) 53.21 50.07 58.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_PYODERMAGANGRENOSUM – Pyoderma gangrenosum
GWS hits:

Survival analyses between endpoints

Plot

before Pyoderma gangrenosum
after Pyoderma gangrenosum

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Drugs most likely to be purchased after Pyoderma gangrenosum

Endpoint not on priority list, no data to show.