No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L29
Hospital discharge: ICD-9 698[0-1]|698[8-9]
Hospital discharge: ICD-8 698[0-1]|6989
Cause of death: ICD-10 L29
Cause of death: ICD-9 698[0-1]|698[8-9]
Cause of death: ICD-8 698[0-1]|6989

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L20-L30
Name in latin Pruritus

Summary Statistics

Key figures

All Female Male
Number of individuals 3315 2383 932
Unadjusted prevalence (%) 0.80 1.04 0.51
Mean age at first event (years) 54.19 51.43 61.24


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.46 [1.56, 3.87] 1.0e-4 404
15 years 0.01 1.37 [0.89, 2.11] 1.6e-1 163
5 years 0.00 3.28 [2.35, 4.59] 2.8e-12 141
1 year 0.00 7.24 [5.11, 10.26] 7.5e-29 65

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: L12_PRURITUS – Pruritus
GWS hits: 1

Survival analyses between endpoints


before Pruritus
after Pruritus

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Drugs most likely to be purchased after Pruritus

Endpoint not on priority list, no data to show.