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Other melanin hyperpigmentation

DOID EFO MESH Endpoint Browser PheWeb

L12_OTHERMELANIN

obsolete_incontinentia pigmenti achromians: a dermal melanocytic condition affecting the shoulder area. Nevus of Ito often occurs in association with nevus of Ota in the same patient but is much less common, although the true incidence is unknown.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L81.4
Hospital discharge: ICD-9 7090G
Cause of death: ICD-10 L81.4
Cause of death: ICD-9 7090G

2 out of 7 registries used, show all original rules.

576

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Check minimum number of events None

576

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Include endpoints None

576

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Remove individuals based on genotype QC

553

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L12_OTHERMELANIN

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L81
Name in latin Alia hyperpigmentatio melaninalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 553 362 191
Unadjusted prevalence (%) 0.13 0.16 0.11
Mean age at first event (years) 63.04 61.89 65.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.56 [0.73, 3.35] 2.5e-1 45
15 years 0.01 0.73 [0.32, 1.66] 4.5e-1 19
5 years 0.00 2.72 [1.36, 5.47] 4.9e-3 19
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_OTHERMELANIN – Other melanin hyperpigmentation
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other melanin hyperpigmentation
after Other melanin hyperpigmentation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other melanin hyperpigmentation

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Endpoint not on priority list, no data to show.