Infections of the skin and subcutaneous tissue

DOID EFO MESH SNOMED Endpoint Browser PheWeb

L12_INFECT_SKIN

Tuberculosis, Cutaneous: Tuberculosis of the skin. It includes scrofuloderma and tuberculid, but not LUPUS VULGARIS.

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L00-L08

Cause of death: ICD-10 L00-L08

2 out of 7 registries used, show all original rules.

20920

Check minimum number of events None

20920

Include endpoints

L12_STAPHSCALDSKIN

L12_IMPETIGO

L12_ABSCESS_CUT

L12_CELLULITIS

L12_LYMPHADENITIS

L12_PILONIDALCYST

L12_INFECT_SKIN_OTHER

24394

Remove individuals based on genotype QC

23513

L12_INFECT_SKIN

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	L12_INFECT_SKIN
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	L12_STAPHSCALDSKIN\|L12_IMPETIGO\|L12_ABSCESS_CUT\|L12_CELLULITIS\|L12_LYMPHADENITIS\|L12_PILONIDALCYST\|L12_INFECT_SKIN_OTHER
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L0
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L0
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Infections of the skin and subcutaneous tissue based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	23513	11492	12021
Unadjusted prevalence (%)	5.71	4.99	6.61
Mean age at first event (years)	45.01	43.42	46.53

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	3.84 [3.18, 4.64]	2.1e-44	2567
15 years	0.01	2.00 [1.70, 2.36]	1.4e-16	843
5 years	0.01	4.91 [4.28, 5.64]	<1e-100	784
1 year	0.00	14.52 [12.40, 17.02]	<1e-100	518

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_INFECT_SKIN – Infections of the skin and subcutaneous tissue
GWS hits: 2

Survival analyses between endpoints

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Plot

before Infections of the skin and subcutaneous tissue
after Infections of the skin and subcutaneous tissue

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Table

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Drugs most likely to be purchased after Infections of the skin and subcutaneous tissue

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Endpoint not on priority list, no data to show.

≡ Risteys

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