Granulomatous disorders of skin and subcutaneous tissue

DOID EFO MESH SNOMED Endpoint Browser PheWeb

L12_GRANULOMATOUSSKIN

Tuberculosis, Cutaneous: Tuberculosis of the skin. It includes scrofuloderma and tuberculid, but not LUPUS VULGARIS.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L92

Cause of death: ICD-10 L92

2 out of 7 registries used, show all original rules.

748

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Check minimum number of events None

748

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Include endpoints

L12_NECROLIPOIDIC

L12_FOREIGNBODYGRANULOMA

L12_GRANULOMASKINNAS

774

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Remove individuals based on genotype QC

747

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L12_GRANULOMATOUSSKIN

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L80-L99

Name in latin Morbositates granulomatosae cutis et telae subcutaneae

NAME	L12_GRANULOMATOUSSKIN
CONTROL_EXCLUDE	L12_OTHERSKINSUBCUTIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	L12_GRANUANNU\|L12_NECROLIPOIDIC\|L12_GRANUFASC\|L12_FOREIGNBODYGRANULOMA\|L12_GRANULOMASKINNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L92
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L92
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Granulomatous disorders of skin and subcutaneous tissue based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	747	559	188
Unadjusted prevalence (%)	0.18	0.24	0.10
Mean age at first event (years)	47.70	45.57	54.04

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	1.76 [0.59, 5.27]	3.1e-1	63
15 years	0.01	1.29 [0.47, 3.56]	6.3e-1	31
5 years	0.00	1.93 [0.80, 4.65]	1.4e-1	12
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_GRANULOMATOUSSKIN – Granulomatous disorders of skin and subcutaneous tissue
GWS hits: 1

Survival analyses between endpoints

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Plot

before Granulomatous disorders of skin and subcutaneous tissue
after Granulomatous disorders of skin and subcutaneous tissue

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Table

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Drugs most likely to be purchased after Granulomatous disorders of skin and subcutaneous tissue

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Endpoint not on priority list, no data to show.