Other epidermal thickening

MESH Endpoint Browser PheWeb

L12_EPIDERMALTHICKOTH

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L85

Cause of death: ICD-10 L85

2 out of 7 registries used, show all original rules.

1242

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Check minimum number of events None

1242

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Include endpoints

L12_KERATPUNCTATA

L12_EPIDERMTHICKNAS

1299

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Remove individuals based on genotype QC

1244

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L12_EPIDERMALTHICKOTH

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L80-L99

Name in latin Alia crassificatio epidermidis

NAME	L12_EPIDERMALTHICKOTH
CONTROL_EXCLUDE	L12_OTHERSKINSUBCUTIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	L12_ACQICTHY\|L12_ACQKERAT\|L12_KERATPUNCTATA\|L12_XEROSCUT\|L12_EPIDERMTHICKNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L85
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L85
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Other epidermal thickening based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1244	671	573
Unadjusted prevalence (%)	0.30	0.29	0.32
Mean age at first event (years)	55.48	52.85	58.57

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.10	5.24 [3.20, 8.56]	4.1e-11	163
15 years	0.02	2.80 [1.91, 4.10]	1.4e-7	65
5 years	0.01	5.31 [3.53, 8.01]	1.5e-15	55
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_EPIDERMALTHICKOTH – Other epidermal thickening
GWS hits:

Survival analyses between endpoints

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Plot

before Other epidermal thickening
after Other epidermal thickening

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Table

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Drugs most likely to be purchased after Other epidermal thickening

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Endpoint not on priority list, no data to show.