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Chronic ulcer of skin, not elsewhere classified

DOID EFO MESH Endpoint Browser PheWeb

L12_CHRONICULCEROFSKIN

chronic ulcer of skin: ['Chronic skin ulceration is a common complication of diabetes, peripheral vascular disease, and disorders that decrease mobility. Local ulcer care will be successful only if the underlying cause is correctly identified and steps are taken to reverse it.']

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L98.4
Hospital discharge: ICD-9 707[8-9]
Hospital discharge: ICD-8 707
Hospital discharge: excluded ICD-8 70700
Cause of death: ICD-10 L98.4
Cause of death: ICD-9 707[8-9]
Cause of death: ICD-8 707
Cause of death: excluded ICD-8 70700

2 out of 7 registries used, show all original rules.

2052

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Check minimum number of events None

2052

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Include endpoints None

2052

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Remove individuals based on genotype QC

2001

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L12_CHRONICULCEROFSKIN

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L98
Name in latin Ulcus chronicum cutis non alibi classificatum

Summary Statistics

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Key figures

All Female Male
Number of individuals 2001 917 1084
Unadjusted prevalence (%) 0.49 0.40 0.60
Mean age at first event (years) 62.34 61.11 63.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 5.10 [3.32, 7.85] 1.2e-13 551
15 years 0.01 1.80 [1.25, 2.61] 1.8e-3 146
5 years 0.01 6.42 [4.87, 8.45] 8.2e-40 223
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_CHRONICULCEROFSKIN – Chronic ulcer of skin, not elsewhere classified
GWS hits: 1

Survival analyses between endpoints

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Plot

before Chronic ulcer of skin, not elsewhere classified
after Chronic ulcer of skin, not elsewhere classified

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chronic ulcer of skin, not elsewhere classified

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Endpoint not on priority list, no data to show.