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Other diseases of pancreas

DOID EFO MESH SNOMED Endpoint Browser PheWeb

K11_PANCOTH

pancreas disease: A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms. [ NCIT:C26842 ]

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K86.2, K86.3, K86.8, K86.9
Hospital discharge: ICD-9 577[2-9]
Hospital discharge: ICD-8 5779
Cause of death: ICD-10 K86.2, K86.3, K86.8, K86.9
Cause of death: ICD-9 577[2-9]
Cause of death: ICD-8 5779

2 out of 7 registries used, show all original rules.

2072

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Check minimum number of events None

2072

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Include endpoints None

2072

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Remove individuals based on genotype QC

2019

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K11_PANCOTH

Control definitions

Control exclude K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2019 871 1148
Unadjusted prevalence (%) 0.49 0.38 0.63
Mean age at first event (years) 59.47 60.35 58.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 6.31 [4.43, 9.00] 2.5e-24 349
15 years 0.02 3.23 [2.41, 4.34] 5.6e-15 131
5 years 0.01 7.59 [5.84, 9.87] 9.8e-52 111
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_PANCOTH – Other diseases of pancreas
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other diseases of pancreas
after Other diseases of pancreas

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Drugs most likely to be purchased after Other diseases of pancreas

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Endpoint not on priority list, no data to show.