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Other diseases of oesophagus

DOID EFO MESH SNOMED Endpoint Browser PheWeb

K11_OTHDISOES

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K22.4, K22.5, K22.6, K22.7, K22.8, K22.9
Hospital discharge: ICD-9 530[5-9]
Hospital discharge: ICD-8 5302|5309
Hospital discharge: excluded ICD-10 K22.7
Cause of death: ICD-10 K22.4, K22.5, K22.6, K22.7, K22.8, K22.9
Cause of death: ICD-9 530[5-9]
Cause of death: ICD-8 5302|5309

2 out of 7 registries used, show all original rules.

3266

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Check minimum number of events None

3266

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Include endpoints None

3266

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Remove individuals based on genotype QC

3175

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K11_OTHDISOES

Control definitions

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3175 1388 1787
Unadjusted prevalence (%) 0.77 0.60 0.98
Mean age at first event (years) 54.53 52.79 55.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.46 [1.02, 2.08] 3.6e-2 694
15 years 0.01 1.03 [0.78, 1.36] 8.5e-1 280
5 years 0.00 2.07 [1.63, 2.63] 3.0e-9 169
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_OTHDISOES – Other diseases of oesophagus
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other diseases of oesophagus
after Other diseases of oesophagus

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Drugs most likely to be purchased after Other diseases of oesophagus

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Endpoint not on priority list, no data to show.