Molar incisor enamel hypoplasia

Endpoint Browser PheWeb

K11_MIH

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Primary healthcare outpatient: ICD-10: K00.40, K00.41

Hospital Discharge: ICD-10 K00.40, K00.41

Cause of death: ICD-10 K00.40, K00.41

3 out of 7 registries used, show all original rules.

727

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Check minimum number of events None

727

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Include endpoints

K11_HYPOPLASIA_ENAMEL_INCLAVO

K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO

727

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Remove individuals based on genotype QC

676

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K11_MIH

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF10

NAME	K11_MIH
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	K11_HYPOPLASIA_ENAMEL_INCLAVO\|K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD	K004[0-1]
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K004[0-1]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K004[0-1]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Molar incisor enamel hypoplasia based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	676	455	221
Unadjusted prevalence (%)	0.16	0.20	0.12
Mean age at first event (years)	20.66	22.80	16.23

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_MIH – Molar incisor enamel hypoplasia
GWS hits: 1

Survival analyses between endpoints

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Plot

before Molar incisor enamel hypoplasia
after Molar incisor enamel hypoplasia

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Table

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Drugs most likely to be purchased after Molar incisor enamel hypoplasia

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Endpoint not on priority list, no data to show.