Paralytic ileus and intestinal obstruction

K11_ILEUS

intestinal pseudo-obstruction: A type of ILEUS, a functional not mechanical obstruction of the INTESTINES. This syndrome is caused by a large number of disorders involving the smooth muscles (MUSCLE, SMOOTH) or the NERVOUS SYSTEM.

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K56

Cause of death: ICD-10 K56

2 out of 7 registries used, show all original rules.

8561

Check minimum number of events None

8561

Include endpoints

K11_PARALIL

K11_INTUSS

K11_VOLVU

K11_IMPACT

K11_ADHE

K11_OTHILEUS

9707

Remove individuals based on genotype QC

9391

K11_ILEUS

Control definitions

Control exclude K11_INTESTOTH

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K55-K63

Name in latin Ileus paralyticus sive obstructio intestini sine hernia

NAME	K11_ILEUS
CONTROL_EXCLUDE	K11_INTESTOTH
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	K11_PARALIL\|K11_INTUSS\|K11_VOLVU\|K11_IMPACT\|K11_ADHE\|K11_OTHILEUS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K56
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K56
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Paralytic ileus and intestinal obstruction based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	9391	4583	4808
Unadjusted prevalence (%)	2.28	1.99	2.65
Mean age at first event (years)	59.73	56.71	62.61

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	3.93 [3.11, 4.97]	3.2e-30	2546
15 years	0.01	1.34 [1.08, 1.66]	7.6e-3	614
5 years	0.01	3.87 [3.28, 4.55]	6.8e-59	679
1 year	0.01	26.06 [22.53, 30.15]	<1e-100	1020

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_ILEUS – Paralytic ileus and intestinal obstruction
GWS hits:

Survival analyses between endpoints

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Plot

before Paralytic ileus and intestinal obstruction
after Paralytic ileus and intestinal obstruction

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Table

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Drugs most likely to be purchased after Paralytic ileus and intestinal obstruction

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Endpoint not on priority list, no data to show.

≡ Risteys

R10

R9

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