Dentofacial anomalies [including malocclusion]

K11_DENTOFACIAL_ANOMALIES

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K07
Cause of death: ICD-10 K07

2 out of 7 registries used, show all original rules.

11368

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Check minimum number of events None

11368

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Include endpoints None

11368

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Remove individuals based on genotype QC

10968

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K11_DENTOFACIAL_ANOMALIES

Control definitions

Control exclude K11_ORAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Similar endpoints

List of similar endpoints to Dentofacial anomalies [including malocclusion] based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 10968 7924 3044
Unadjusted prevalence (%) 2.66 3.44 1.67
Mean age at first event (years) 43.20 42.64 44.65

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.30 [0.87, 1.94] 2.0e-1 326
15 years 0.01 0.93 [0.64, 1.35] 7.0e-1 143
5 years 0.00 2.02 [1.35, 3.02] 6.8e-4 84
1 year 0.00 2.98 [1.75, 5.08] 5.6e-5 22

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_DENTOFACIAL_ANOMALIES – Dentofacial anomalies [including malocclusion]
GWS hits:

Survival analyses between endpoints

Plot

before Dentofacial anomalies [including malocclusion]
after Dentofacial anomalies [including malocclusion]

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Drugs most likely to be purchased after Dentofacial anomalies [including malocclusion]

Endpoint not on priority list, no data to show.