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Achalasia of cardia

DOID MESH Endpoint Browser PheWeb

K11_ACHAL

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K22.0
Hospital discharge: ICD-9 5300
Hospital discharge: ICD-8 5300
Cause of death: ICD-10 K22.0
Cause of death: ICD-9 5300
Cause of death: ICD-8 5300

2 out of 7 registries used, show all original rules.

553

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Check minimum number of events None

553

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Include endpoints None

553

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Remove individuals based on genotype QC

540

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K11_ACHAL

Control definitions

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K22
Name in latin Achalasia cardiae

Summary Statistics

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Key figures

All Female Male
Number of individuals 540 274 266
Unadjusted prevalence (%) 0.13 0.12 0.15
Mean age at first event (years) 50.18 47.03 53.43

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.83 [1.56, 5.13] 6.4e-4 84
15 years 0.01 1.63 [0.95, 2.81] 7.9e-2 33
5 years 0.01 3.48 [2.03, 5.96] 5.5e-6 22
1 year 0.00 10.85 [5.73, 20.54] 2.5e-13 13

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_ACHAL – Achalasia of cardia
GWS hits: 1

Survival analyses between endpoints

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Plot

before Achalasia of cardia
after Achalasia of cardia

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Drugs most likely to be purchased after Achalasia of cardia

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Endpoint not on priority list, no data to show.