Pain in joint


No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M25.5
Hospital discharge: ICD-8 7873
Cause of death: ICD-10 M25.5
Cause of death: ICD-8 7873

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude PAIN

Extra metadata

First used in FinnGen datafreeze DF3
Parent code in ICD-10 M25
Name in latin Arthralgia

Summary Statistics

Key figures

All Female Male
Number of individuals 30614 21232 9382
Unadjusted prevalence (%) 7.43 9.22 5.16
Mean age at first event (years) 47.34 46.06 50.22


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.68 [1.35, 2.09] 3.0e-6 1334
15 years 0.01 1.21 [1.00, 1.46] 5.0e-2 609
5 years 0.00 2.26 [1.90, 2.68] 9.2e-21 327
1 year 0.00 4.05 [3.21, 5.11] 4.6e-32 111

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: JOINTPAIN – Pain in joint
GWS hits: 5

Survival analyses between endpoints


before Pain in joint
after Pain in joint

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Drugs most likely to be purchased after Pain in joint

Endpoint not on priority list, no data to show.