Pulmonary eosinophilia, not elsewhere classified

J10_PULMEOS

eosinophilic pneumonia: An inflammatory lung disorder characterized by an increased number of eosinophils in the lungs. The majority of cases are idiopathic, without identifiable cause. In a minority of cases, medications, fungal infections, and environmental triggers have been implicated. It manifests as acute or chronic. Acute eosinophilic pneumonia is a severe and rapidly progressing pneumonia that may lead to respiratory failure requiring mechanical ventilation. Chronic eosinophilic pneumonia follows a slower course and manifests as fever, dyspnea, cough, and weight loss.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J82
Hospital discharge: ICD-9 5183
Hospital discharge: ICD-8 51920
Cause of death: ICD-10 J82
Cause of death: ICD-9 5183
Cause of death: ICD-8 51920

2 out of 7 registries used, show all original rules.

362

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Check minimum number of events None

362

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Include endpoints None

362

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Remove individuals based on genotype QC

349

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J10_PULMEOS

Control definitions

Control exclude J10_INTERSTITIUM

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 J80-J84
Name in latin Eosinophilia pulmonum non alibi classificata

Summary Statistics

Key figures

All Female Male
Number of individuals 349 193 156
Unadjusted prevalence (%) 0.08 0.08 0.09
Mean age at first event (years) 55.77 53.20 58.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_PULMEOS – Pulmonary eosinophilia, not elsewhere classified
GWS hits:

Survival analyses between endpoints

Plot

before Pulmonary eosinophilia, not elsewhere classified
after Pulmonary eosinophilia, not elsewhere classified

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Drugs most likely to be purchased after Pulmonary eosinophilia, not elsewhere classified

Endpoint not on priority list, no data to show.