Other acute lower respiratory infections

J10_LOWERINF

bronchitis: An acute or chronic inflammatory process affecting the bronchi. [database_cross_reference: NCIT:C2911]

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J20-J22
Cause of death: ICD-10 J20-J22

2 out of 7 registries used, show all original rules.

19884

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Check minimum number of events None

19884

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Remove individuals based on genotype QC

22873

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J10_LOWERINF

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 22873 11044 11829
Unadjusted prevalence (%) 5.55 4.80 6.51
Mean age at first event (years) 48.28 46.47 49.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 5.01 [4.21, 5.97] 1.9e-73 5125
15 years 0.01 2.00 [1.73, 2.31] 1.2e-20 1530
5 years 0.01 5.07 [4.60, 5.59] <1e-100 1962
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_LOWERINF – Other acute lower respiratory infections
GWS hits: 5

Survival analyses between endpoints

Plot

before Other acute lower respiratory infections
after Other acute lower respiratory infections

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Drugs most likely to be purchased after Other acute lower respiratory infections

Endpoint not on priority list, no data to show.