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All influenza (not pneumonia)

DOID EFO MESH SNOMED Endpoint Browser PheWeb

INFLUENZA

influenza: An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J10, J11
Hospital discharge: ICD-9 487
Hospital discharge: ICD-8 47[0-4]
Hospital discharge: excluded ICD-10 J10.0, J11.0
Hospital discharge: excluded ICD-9 4870
Hospital discharge: excluded ICD-8 471
Cause of death: ICD-10 J10, J11
Cause of death: ICD-9 487
Cause of death: ICD-8 47[0-4]
Cause of death: excluded ICD-10 4870
Cause of death: excluded ICD-9 471

2 out of 7 registries used, show all original rules.

5771

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Check minimum number of events None

5771

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Include endpoints None

5771

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Remove individuals based on genotype QC

5544

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INFLUENZA

Control definitions

Control exclude J10_INFLUPNEU

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 5544 2346 3198
Unadjusted prevalence (%) 1.35 1.02 1.76
Mean age at first event (years) 43.98 48.13 40.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 4.39 [3.49, 5.53] 2.6e-36 760
15 years 0.01 1.33 [1.05, 1.69] 1.7e-2 166
5 years 0.01 4.99 [3.53, 7.06] 9.6e-20 292
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: INFLUENZA – All influenza (not pneumonia)
GWS hits: 1

Survival analyses between endpoints

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Plot

before All influenza (not pneumonia)
after All influenza (not pneumonia)

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Drugs most likely to be purchased after All influenza (not pneumonia)

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Endpoint not on priority list, no data to show.