Rheumatic valve diseases

DOID EFO MESH SNOMED Endpoint Browser PheWeb

I9_RHEUVALV

tricuspid valve disease: A disease involving the tricuspid valve.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I05, I06, I07, I08

Hospital discharge: ICD-9 39[4-6]

Hospital discharge: ICD-8 3940|3950|3960|3970

Cause of death: ICD-10 I05, I06, I07, I08

Cause of death: ICD-9 39[4-6]

Cause of death: ICD-8 3940|3950|3960|3970

2 out of 7 registries used, show all original rules.

782

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Check minimum number of events None

782

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Include endpoints None

782

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Remove individuals based on genotype QC

741

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I9_RHEUVALV

Control definitions

Control exclude I9_RHEUFEV

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

NAME	I9_RHEUVALV
CONTROL_EXCLUDE	I9_RHEUFEV
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	I0[5-8]
HD_ICD_9	39[4-6]
HD_ICD_8	3940\|3950\|3960\|3970
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	I0[5-8]
COD_ICD_9	39[4-6]
COD_ICD_8	3940\|3950\|3960\|3970
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Rheumatic valve diseases based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	741	310	431
Unadjusted prevalence (%)	0.18	0.13	0.24
Mean age at first event (years)	54.20	51.30	56.28

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.65 [0.83, 3.30]	1.5e-1	344
15 years	0.01	1.10 [0.67, 1.80]	7.0e-1	123
5 years	0.00	2.20 [1.53, 3.17]	2.2e-5	75
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_RHEUVALV – Rheumatic valve diseases
GWS hits:

Survival analyses between endpoints

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Plot

before Rheumatic valve diseases
after Rheumatic valve diseases

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Table

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Drugs most likely to be purchased after Rheumatic valve diseases

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Endpoint not on priority list, no data to show.