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Other peripheral vascular diseases

DOID EFO MESH SNOMED Endpoint Browser PheWeb

I9_OTHPER

peripheral arterial disease: A disorder of the arteries supplying the upper and lower extremity and the visceral organs. This includes the mesenteric arteries, the renal arteries and the aorta and excludes cerebrovascular arterial disease. Patients experience cramping and pain usually in the calves and thighs while walking. The symptoms subside with rest.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I73
Hospital discharge: ICD-9 443
Hospital discharge: ICD-8 443
Cause of death: ICD-10 I73
Cause of death: ICD-9 443
Cause of death: ICD-8 443

2 out of 7 registries used, show all original rules.

2548

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Check minimum number of events None

2548

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Include endpoints

2548

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Remove individuals based on genotype QC

2489

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I9_OTHPER

Control definitions

Control exclude I9_DOAAC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I70-I79
Name in latin Alii morbi vasorum periphericorum

Summary Statistics

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Key figures

All Female Male
Number of individuals 2489 1533 956
Unadjusted prevalence (%) 0.60 0.67 0.53
Mean age at first event (years) 50.66 46.70 57.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.45 [1.66, 3.61] 7.0e-6 415
15 years 0.01 1.65 [1.28, 2.14] 1.2e-4 183
5 years 0.00 2.46 [1.90, 3.19] 1.2e-11 94
1 year 0.00 4.71 [3.26, 6.82] 2.0e-16 37

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_OTHPER – Other peripheral vascular diseases
GWS hits:

Survival analyses between endpoints

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Plot

before Other peripheral vascular diseases
after Other peripheral vascular diseases

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Drugs most likely to be purchased after Other peripheral vascular diseases

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Endpoint not on priority list, no data to show.