Other other unspecified disorders of the circulatory system

I9_OTHOTH

cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I97, I98*, I99
Hospital discharge: ICD-9 4590A|459[8-9]
Hospital discharge: ICD-8 4581|4589
Cause of death: ICD-10 I97, I98*, I99
Cause of death: ICD-9 4590A|459[8-9]
Cause of death: ICD-8 4581|4589

2 out of 7 registries used, show all original rules.

1097

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Check minimum number of events None

1097

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Include endpoints None

1097

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Remove individuals based on genotype QC

1081

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I9_OTHOTH

Control definitions

Control exclude I9_OTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1081 585 496
Unadjusted prevalence (%) 0.26 0.25 0.27
Mean age at first event (years) 57.94 56.78 59.30

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.03 [1.57, 5.86] 9.8e-4 215
15 years 0.02 2.07 [1.34, 3.20] 1.0e-3 92
5 years 0.01 3.60 [2.46, 5.26] 4.0e-11 51
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_OTHOTH – Other other unspecified disorders of the circulatory system
GWS hits:

Survival analyses between endpoints

Plot

before Other other unspecified disorders of the circulatory system
after Other other unspecified disorders of the circulatory system

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Drugs most likely to be purchased after Other other unspecified disorders of the circulatory system

Endpoint not on priority list, no data to show.