Non-ischemic cardiomyopathy

I9_NONISCHCARDMYOP

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

not I9_IHD

357889

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

11209

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Remove individuals based on genotype QC

10839

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I9_NONISCHCARDMYOP

Control definitions

Control conditions not I9_IHD

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 10839 4778 6061
Unadjusted prevalence (%) 2.63 2.08 3.33
Mean age at first event (years) 67.87 67.86 67.87

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.00 [2.96, 5.41] 1.8e-19 3735
15 years 0.01 1.76 [1.44, 2.16] 3.6e-8 1200
5 years 0.01 3.95 [3.44, 4.54] 1.2e-84 1215
1 year 0.00 15.14 [13.27, 17.27] <1e-100 1068

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_NONISCHCARDMYOP – Non-ischemic cardiomyopathy
GWS hits: 2

Survival analyses between endpoints

Plot

before Non-ischemic cardiomyopathy
after Non-ischemic cardiomyopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Non-ischemic cardiomyopathy

Endpoint not on priority list, no data to show.