Cardiomyopathy, other and unspecified

I9_CARDMYOOTH

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I42.8, I42.9
Hospital discharge: ICD-9 4259X
Hospital discharge: ICD-8 425
Cause of death: ICD-10 I42.8, I42.9
Cause of death: ICD-9 4259X
Cause of death: ICD-8 425

2 out of 7 registries used, show all original rules.

2656

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Check minimum number of events None

2656

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Include endpoints None

2656

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Remove individuals based on genotype QC

2593

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I9_CARDMYOOTH

Control definitions

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2593 1048 1545
Unadjusted prevalence (%) 0.63 0.46 0.85
Mean age at first event (years) 58.08 58.17 58.02

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 4.89 [2.82, 8.48] 1.6e-8 576
15 years 0.02 2.66 [1.86, 3.81] 9.9e-8 215
5 years 0.01 5.89 [4.51, 7.67] 3.4e-39 188
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CARDMYOOTH – Cardiomyopathy, other and unspecified
GWS hits: 5

Survival analyses between endpoints

Plot

before Cardiomyopathy, other and unspecified
after Cardiomyopathy, other and unspecified

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiomyopathy, other and unspecified

Endpoint not on priority list, no data to show.