Coronary artery bypass grafting

DOID EFO MESH SNOMED Endpoint Browser PheWeb

I9_CABG

Coronary Vasospasm: Sudden coronary artery smooth muscle contraction leading to lumen constriction and decreased blood flow.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Operations: NOMESCO codes ^FNA|^FNB|^FNC|^FND|^FNE

Operations: Finnish Hospital League codes ^5311$|^5312$|^5313$|^5314$|^5315$

Operations: Heart Patient codes v1 ^11|^25$

Operations: Heart Patient codes v2 ^AA1|^AA2|^AA3|^AAX

1 out of 7 registries used, show all original rules.

11957

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Check minimum number of events None

11957

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Include endpoints None

11957

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Remove individuals based on genotype QC

11582

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I9_CABG

Control definitions

Control exclude I9_ISCHHEART

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF10

NAME	I9_CABG
CONTROL_EXCLUDE	I9_ISCHHEART
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM	^FNA\|^FNB\|^FNC\|^FND\|^FNE
OPER_HL	^5311$\|^5312$\|^5313$\|^5314$\|^5315$
OPER_HP1	^11\|^25$
OPER_HP2	^AA1\|^AA2\|^AA3\|^AAX
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Coronary artery bypass grafting based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	11582	1888	9694
Unadjusted prevalence (%)	2.81	0.82	5.33
Mean age at first event (years)	64.47	66.29	64.11

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	1.94 [1.64, 2.30]	2.8e-14	4321
15 years	0.01	1.60 [1.42, 1.80]	2.2e-14	2297
5 years	0.00	1.71 [1.53, 1.91]	3.2e-21	735
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CABG – Coronary artery bypass grafting
GWS hits: 74

Survival analyses between endpoints

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Plot

before Coronary artery bypass grafting
after Coronary artery bypass grafting

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Table

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Drugs most likely to be purchased after Coronary artery bypass grafting

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Endpoint not on priority list, no data to show.