Coronary artery bypass grafting

I9_CABG

Coronary Vasospasm: Sudden coronary artery smooth muscle contraction leading to lumen constriction and decreased blood flow.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Operations: NOMESCO codes ^FNA|^FNB|^FNC|^FND|^FNE
Operations: Finnish Hospital League codes ^5311$|^5312$|^5313$|^5314$|^5315$
Operations: Heart Patient codes v1 ^11|^25$
Operations: Heart Patient codes v2 ^AA1|^AA2|^AA3|^AAX

1 out of 7 registries used, show all original rules.

11957

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Check minimum number of events None

11957

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Include endpoints None

11957

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Remove individuals based on genotype QC

11582

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I9_CABG

Control definitions

Control exclude I9_ISCHHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF10

Summary Statistics

Key figures

All Female Male
Number of individuals 11582 1888 9694
Unadjusted prevalence (%) 2.81 0.82 5.33
Mean age at first event (years) 64.47 66.29 64.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.94 [1.64, 2.30] 2.8e-14 4321
15 years 0.01 1.60 [1.42, 1.80] 2.2e-14 2297
5 years 0.00 1.71 [1.53, 1.91] 3.2e-21 735
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CABG – Coronary artery bypass grafting
GWS hits: 74

Survival analyses between endpoints

Plot

before Coronary artery bypass grafting
after Coronary artery bypass grafting

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Coronary artery bypass grafting

Endpoint not on priority list, no data to show.