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Other, unspecified and serous retinal detachments

DOID EFO MESH SNOMED Endpoint Browser PheWeb

H7_RETINALDETACHOTH

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H33.2, H33.5
Hospital discharge: ICD-9 361[8-9]
Hospital discharge: ICD-8 376
Hospital discharge: excluded ICD-8 37602
Cause of death: ICD-10 H33.2, H33.5
Cause of death: ICD-9 361[8-9]
Cause of death: ICD-8 376
Cause of death: excluded ICD-8 37602

2 out of 7 registries used, show all original rules.

866

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Check minimum number of events None

866

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Include endpoints None

866

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Remove individuals based on genotype QC

849

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H7_RETINALDETACHOTH

Control definitions

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 849 383 466
Unadjusted prevalence (%) 0.21 0.17 0.26
Mean age at first event (years) 55.00 54.17 55.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.70 [1.97, 3.70] 5.9e-10 124
15 years 0.01 1.59 [1.16, 2.20] 4.3e-3 56
5 years 0.00 1.92 [1.19, 3.10] 7.4e-3 27
1 year 0.00 3.95 [2.02, 7.74] 6.1e-5 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINALDETACHOTH – Other, unspecified and serous retinal detachments
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other, unspecified and serous retinal detachments
after Other, unspecified and serous retinal detachments

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other, unspecified and serous retinal detachments

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Endpoint not on priority list, no data to show.