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Retinal detachment with retinal break

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H7_RETINALDETACHBREAK

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H33.0
Hospital discharge: ICD-9 3610
Hospital discharge: ICD-8 37602
Cause of death: ICD-10 H33.0
Cause of death: ICD-9 3610
Cause of death: ICD-8 37602

2 out of 7 registries used, show all original rules.

4148

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Check minimum number of events None

4148

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Include endpoints None

4148

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Remove individuals based on genotype QC

4024

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H7_RETINALDETACHBREAK

Control definitions

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H33
Name in latin Amotio/ablatio retinae cum ruptura

Summary Statistics

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Key figures

All Female Male
Number of individuals 4024 1705 2319
Unadjusted prevalence (%) 0.98 0.74 1.28
Mean age at first event (years) 58.79 56.96 60.13

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.39 [0.87, 2.20] 1.7e-1 528
15 years 0.01 1.15 [0.82, 1.63] 4.2e-1 277
5 years 0.00 1.56 [1.16, 2.09] 3.1e-3 117
1 year 0.00 2.13 [1.39, 3.27] 5.5e-4 29

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINALDETACHBREAK – Retinal detachment with retinal break
GWS hits: 2

Survival analyses between endpoints

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Plot

before Retinal detachment with retinal break
after Retinal detachment with retinal break

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Retinal detachment with retinal break

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Endpoint not on priority list, no data to show.