Dislocation of lens

H7_LENSDISLOCATIO

lens disease: A disease involving the lens of camera-type eye. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H27.1
Hospital discharge: ICD-9 3793B
Hospital discharge: ICD-8 37870
Cause of death: ICD-10 H27.1
Cause of death: ICD-9 3793B
Cause of death: ICD-8 37870

2 out of 7 registries used, show all original rules.

456

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Check minimum number of events None

456

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Include endpoints None

456

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Remove individuals based on genotype QC

443

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H7_LENSDISLOCATIO

Control definitions

Control exclude H7_LENS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 H27
Name in latin Dislocatio lentis

Summary Statistics

Key figures

All Female Male
Number of individuals 443 199 244
Unadjusted prevalence (%) 0.11 0.09 0.13
Mean age at first event (years) 68.79 70.92 67.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.88 [0.79, 4.45] 1.5e-1 98
15 years 0.01 0.86 [0.38, 1.94] 7.2e-1 37
5 years 0.00 2.82 [1.59, 5.02] 4.1e-4 44
1 year 0.00 3.31 [1.55, 7.06] 2.0e-3 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_LENSDISLOCATIO – Dislocation of lens
GWS hits: 1

Survival analyses between endpoints

Plot

before Dislocation of lens
after Dislocation of lens

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Dislocation of lens

Endpoint not on priority list, no data to show.